Sample Syllabus
PD Guide
PowerPoint:
Prader-Willi Syndrome and Angelman Syndrome
This presentation introduces the genetic and developmental foundations of two imprinting disorders caused by abnormalities on chromosome 15q11-q13. It explains how Prader-Willi syndrome (PWS) results from loss of paternal genes, while Angelman syndrome (AS) stems from loss of maternal genes, highlighting their shared biological basis but distinct clinical features. The presentation details the early signs, diagnostic methods, and hallmark characteristics of each disorder—such as hypotonia, hyperphagia, and intellectual disability in PWS, and ataxia, minimal speech, and frequent laughter in AS. Participants explore evidence-based interventions including physical, occupational, and speech therapies, behavioral supports, and family education. Comparative activities and case discussions emphasize early detection, multidisciplinary teamwork, and compassionate, informed care for children and families affected by these rare neurogenetic syndromes.
Case Study
Learning Activities
Multimedia Illustrations
- Title with a description
- Link to video
- Suggested citation
- Length of the video
- EI/ECSE standard
- DEC Recommended Practice
Resources
| Title | Key Content | Link |
| Prader-Willi Syndrome | Overview of PWS including information on genetic imprinting. | View |
| PWS Video | A video describing what it is like to live with PWS from individuals with PWS | View |
| PWS with Dr. Michalec | A podcast interview with Dr. Michalec on PWS and how caregivers and practitioners can help. | View |
| PWS | A podcast of experts on PWD who provide an in-depth look at PWD including diagnosis, treatment, and PWS in the community. | View |
| A Parent’s Early Perspective on PWS | A podcast series of parents sharing their story of having a child with PWS. | View |
| A Son with PWS | A podcast interview of a mother on raising her son with PWS. | View |
| PWS Behavior Challenges and Solutions | Behavior tips for teachers. | View |
| Comparison of Prader-Willi and Angelman Syndrome | Coursera video overview of PWS and AS. | View |
| Genetic Comparison of PWS and AS | An in-depth comparison of the genetics of PWS and AS. | View |
| An Inside Look at Angelman Syndrome Rare Disease: An Interview with Amanda Moore | A podcast interview with Amanda Moore, mother of a child with AS and CEO of the Angelman Syndrome Foundation, on her experiences raising a child with AS. | View |
| RARE Diagnosis: Angelman Syndrome | A podcast interview series of parents of children with AS. | View |
| Angelman Syndrome | A podcast of experts who discuss AS in-depth including diagnosis, treatment, and the strength of the AS community. | View |
| Angelman UK video collection | A collection of videos including communication, behavior, epilepsy, transition, siblings, challenging behaviors, and conferences talks. | View |
